Aging is a natural process that affects everyone, but as fine lines, wrinkles, and sagging skin become more noticeable over time, many seek effective solutions to maintain a youthful appearance.
While aging may be inevitable, its visible effects can be addressed with modern aesthetic treatments that go beyond temporarily masking these signs.
Enter Ellansé, a revolutionary collagen stimulator that has gained popularity in aesthetic medicine, particularly in markets like Singapore where it’s sometimes referred to as “少女针” (translated from Mandarin as the “Needle of Youth”).
Unlike traditional dermal fillers, Ellansé offers both immediate results and long-term benefits by stimulating your body’s natural collagen production.
Related: Dermal Fillers in Singapore: The Comprehensive Guide
This comprehensive guide explores everything you need to know about Ellansé collagen stimulator: how it works, its benefits compared to traditional fillers, treatment areas, longevity, side effects, and what to expect during and after treatment.
What is Ellansé Collagen Stimulator?
Ellansé is a next-generation dermal filler with collagen-stimulating properties. It consists of:
- 30% biodegradable polycaprolactone (PCL) microspheres
- 70% carboxymethylcellulose (CMC) gel carrier
What sets Ellansé apart from traditional hyaluronic acid (HA) fillers is its dual-action mechanism. Not only does it provide immediate volume restoration like conventional fillers, but it also triggers the body’s natural collagen production for longer-lasting results.
Read more: Botox vs Dermal Fillers: Which is Better? (Updated)
How Does Ellansé Work?
Ellansé works through a two-step process that addresses both immediate and long-term concerns:
- Immediate Volume Restoration: The CMC gel carrier provides instant volumization to depleted areas of the face. This component fills in wrinkles and hollows immediately after injection and typically lasts for about 12 weeks.
- Long-lasting Collagen Stimulation: Simultaneously, the PCL microspheres stimulate Type I collagen production (the main type of collagen found in skin). As your body gradually metabolizes the PCL, it creates a scaffolding that encourages new collagen formation. This process peaks at approximately 3 months post-treatment and creates a natural, long-lasting volumization effect.
As we age, our natural collagen production decreases at an average rate of 1.5% annually starting from our 20s.
Related: Dermal Fillers vs Thread Lifts in Singapore: Cost and Comparison
Since collagen is the main structural protein maintaining our skin’s architecture, elasticity, and firmness, this decline leads to common signs of aging.
Ellansé addresses this fundamental issue by stimulating your skin to produce new collagen rather than simply adding temporary volume.
Types of Ellansé Collagen Stimulators
Ellansé is available in different formulations that vary primarily in their longevity. The difference lies in the length of the PCL molecule chains – the longer the chain, the longer the results will last:
| Type | Longevity |
|---|---|
| Ellansé S | At least 18 months |
| Ellansé M | At least 2 years |
| Ellansé L | At least 3 years |
| Ellansé E | At least 4 years (available in some markets) |
Your aesthetic physician will recommend the most appropriate Ellansé type based on your specific needs, desired longevity, and treatment areas.
Ellansé vs. Traditional Fillers: Key Differences
Ellansé differs significantly from conventional hyaluronic acid (HA) fillers in several important ways:
| Feature | Ellansé | Hyaluronic Acid Fillers |
|---|---|---|
| Volume restoration | Immediate | Immediate |
| Volume maintenance | Yes, through collagen stimulation | Gradual decrease as HA breaks down |
| Longevity | 18 months to 3+ years depending on type | 6-18 months |
| Dissolvable | No | Yes, with hyaluronidase |
| Migration risk | Minimal | Yes |
| Delayed hypersensitivity | Very rare | More common (potential for nodules) |
Why Choose Ellansé Over Traditional Fillers?
- Longer-lasting results: With effects lasting up to 3+ years, Ellansé requires fewer maintenance sessions than traditional HA fillers.
- Natural-looking outcomes: The stimulated collagen creates results that look and feel natural.
- Progressive improvement: The appearance continues to enhance over time as collagen production increases.
- Cost-effective in the long run: Despite a higher initial cost, the extended longevity makes it more economical over time.
- Minimal migration risk: Once injected, Ellansé tends to stay where it’s placed rather than spreading to surrounding tissues.
Related: Is Rejuran Healer Treatment in Singapore Safe and Effective? (Updated)
Comparing Collagen Stimulators: Ellansé, Radiesse, and Sculptra
Ellansé is one of several collagen-stimulating fillers available on the market. Here’s how it compares to other popular options:
| Feature | Ellansé | Radiesse | Sculptra |
|---|---|---|---|
| Composition | 30% PCL microspheres + 70% CMC gel | 30% Calcium hydroxylapatite (CaHA) + 70% CMC gel | Poly-L-Lactic acid (PLLA) |
| Result timing | Immediate + progressive | Immediate + progressive | Gradual (over several months) |
| Treatment sessions | Usually one-off | Usually one-off | Multiple (3-4 initial sessions) |
| Longevity | 18 months to 3+ years | 12-18 months | 2-3 years after full treatment |
| Post-treatment | Minimal swelling | More swelling | Requires massage for 5 days |
Ellansé vs. Sculptra: A Closer Look
While both are collagen stimulators, Ellansé and Sculptra work differently:
- Immediate results: Ellansé provides instant volumization plus progressive collagen stimulation, while Sculptra works gradually over months.
- Treatment protocol: Ellansé typically requires just one session, whereas Sculptra needs several treatments spaced about a month apart.
- Post-treatment care: Sculptra requires regular massage post-treatment to prevent nodule formation; Ellansé generally doesn’t.
- Application flexibility: Both can be used complementarily – Ellansé for deeper volume and Sculptra for more superficial skin quality improvement.
Treatment Areas for Ellansé
Ellansé is versatile and can be used to treat various parts of the face to address different aging concerns:
Upper Face
- Temples: Restores volume to hollow temples, which can create a gaunt appearance with age
- Brow area: Lifts and defines the eyebrows
- Forehead: Smoothens concave areas and fine lines
Mid Face
- Cheeks: Restores volume, creating the youthful “apple cheek” effect
- Nose: Can be used for non-surgical rhinoplasty to improve nasal contours
- Nasolabial folds: Softens the lines that run from the nose to the corners of the mouth
Lower Face
- Jawline: Enhances definition and reduces early jowling
- Chin: Improves projection and definition
- Marionette lines: Diminishes the lines from the corners of the mouth to the chin
- Corners of the mouth: Lifts downturned mouth corners
It’s important to note that Ellansé is not recommended for areas with thinner skin such as the lips, eyelids, and under-eye area, as collagen stimulation in these delicate regions may cause visible lumps.
Are You a Suitable Candidate for Ellansé?
Ellansé is generally suitable for adults who want to address facial aging signs like wrinkles, volume loss, and skin laxity. Ideal candidates include those who:
- Want to restore youthful contours to their face
- Prefer longer-lasting results than those offered by traditional fillers
- Have signs of facial aging but aren’t ready for surgical intervention
- Desire improved skin quality along with volume restoration
However, Ellansé may not be appropriate for individuals who:
- Have severe allergies
- Have known hypersensitivity to any components in Ellansé
- Have acute or chronic skin conditions (infection or inflammation)
- Are prone to keloid formation or hypertrophic scarring
- Are currently undergoing cortisone treatment
- Have active infections or sepsis
- Have active or history of autoimmune disorders
The Ellansé Treatment Experience
Before Treatment
- A thorough consultation with your aesthetic physician will determine if you’re suitable for Ellansé
- Your doctor will assess your facial structure, discuss your goals, and recommend the appropriate Ellansé type
- You may be advised to avoid certain medications and supplements that increase bleeding risk, such as aspirin, vitamin E, and fish oil
During Treatment
- The entire procedure typically takes 30-45 minutes
- You’ll need to remove any makeup before treatment
- The injection sites will be marked and cleansed with antiseptic
- A topical numbing cream will be applied to minimize discomfort
- Using a fine needle or cannula, your doctor will inject small amounts of Ellansé into the targeted areas
- Some physicians may gently massage the treated areas to ensure even distribution
After Treatment
- You can resume normal activities immediately after treatment
- Some temporary swelling, redness, or bruising at the injection sites is normal
- These side effects typically resolve within a few days, though in some cases may take 1-2 weeks to fully dissipate
- Your doctor may prescribe medication to manage swelling and discomfort
Aftercare Guidelines
To ensure optimal results and minimize complications:
Do’s:
- Use ice packs to reduce swelling and bruising
- Wash your hands before touching the treated areas
- Follow your doctor’s specific aftercare instructions
Don’ts:
- Avoid massaging your face after treatment (unless specifically instructed)
- Avoid applying makeup for at least 24 hours post-treatment
- Avoid strenuous exercise, sun exposure, and heat (saunas, hot tubs) for 3 days
- Avoid alcohol and blood-thinning medications for 12-48 hours after treatment
Results and Longevity
Immediate and Progressive Results
Thanks to the CMC gel carrier, you’ll notice volume restoration immediately after Ellansé treatment. The collagen-stimulating effects then gradually develop, with results typically peaking around 3 months post-treatment as your body produces more collagen.
How Long Do Results Last?
Ellansé provides semi-permanent results that vary depending on the type used:
- Ellansé S: At least 18 months
- Ellansé M: At least 2 years
- Ellansé L: At least 3 years
- Ellansé E: Up to 4 years (where available)
Remember that individual factors such as age, metabolism, lifestyle, and the treatment area can influence how long your results last.
Can Ellansé Be Reversed?
Unlike hyaluronic acid fillers that can be dissolved with hyaluronidase, Ellansé cannot be dissolved or reversed after injection. This is why it’s crucial to choose an experienced and skilled practitioner who can ensure optimal results.
Safety Profile and Side Effects
Regulatory Status
While Ellansé is not FDA-approved in the US, it has received CE marking in Europe since 2009 (indicating it meets European safety standards) and is approved by Singapore’s Health Sciences Authority (HSA). The components of Ellansé (PCL and CMC) are classified by the FDA as Generally Recognized As Safe (GRAS) substances and have been used in medical applications for many years.
Common Side Effects
Most side effects associated with Ellansé are mild and transient:
- Localized redness
- Swelling
- Bruising
- Tenderness at injection sites
These typically resolve within a few days to weeks without intervention.
Rare Complications
Though uncommon, more serious side effects may include:
- Infection
- Pain at the injection site
- Nodule formation
- Secondary edema (fluid accumulation)
If you experience any concerning symptoms after treatment, contact your doctor immediately.
Cost of Ellansé Treatment
The cost of Ellansé treatment varies depending on several factors:
- The type of Ellansé used (S, M, L, or E)
- The number of syringes required
- The treatment areas
- The expertise of the practitioner
- Geographic location
In Singapore, for example, Ellansé typically costs between $1,200 to $1,800 per treatment, with package options often available for multiple syringes. While this is higher than the cost of traditional HA fillers ($800-$1,000 per syringe), the longer-lasting results of Ellansé can make it more cost-effective in the long run.
Note that as an elective cosmetic procedure, Ellansé treatments are not covered by medical insurance or Medisave.
Conclusion: Is Ellansé Right for You?
Ellansé represents a significant advancement in facial rejuvenation technology, offering both immediate and long-lasting results through its unique collagen-stimulating properties. Its ability to provide natural-looking volume restoration while simultaneously improving skin quality makes it an attractive option for those seeking comprehensive facial rejuvenation without surgery.
However, the decision to use Ellansé should be made carefully, taking into consideration:
- Your aesthetic goals
- The permanence of the treatment
- The importance of choosing a skilled and experienced practitioner
- Your medical history and contraindications
As with any aesthetic procedure, a thorough consultation with a qualified medical professional is essential to determine if Ellansé is the right choice for you. They can create a customized treatment plan that addresses your specific concerns and helps you achieve natural, harmonious results that enhance your appearance while maintaining your unique facial character.
Frequently Asked Questions (FAQ)
How does Ellansé differ from traditional hyaluronic acid fillers?
Ellansé contains polycaprolactone (PCL) microspheres that stimulate your body’s natural collagen production, providing both immediate volumization and long-term skin improvements. Traditional HA fillers only provide temporary volume that gradually diminishes as the body absorbs the hyaluronic acid. Ellansé results last significantly longer (18 months to 3+ years versus 6-18 months for HA fillers).
Is Ellansé treatment painful?
Most patients report minimal discomfort during Ellansé treatment. Your doctor will apply a topical anesthetic cream before the procedure, and in some cases, may use local anesthetic injections for additional comfort. The Ellansé formula itself does not contain lidocaine, unlike some HA fillers.
How soon will I see results from Ellansé?
You’ll notice immediate volume restoration right after treatment due to the CMC gel carrier. The collagen-stimulating benefits develop gradually over the following weeks, with optimal results typically visible around 3 months post-treatment as collagen production increases.
Is there any downtime after Ellansé treatment?
Ellansé treatment involves minimal downtime. Most patients can resume normal activities immediately after the procedure. Some temporary swelling, redness, or bruising may occur at the injection sites but typically subsides within a few days.
Can Ellansé be used with other aesthetic treatments?
Yes, Ellansé can be effectively combined with other treatments such as botulinum toxin injections, skin boosters, or energy-based devices like HIFU or lasers. Your doctor can design a comprehensive treatment plan that incorporates multiple modalities for optimal rejuvenation.
What happens if I don’t like my results from Ellansé?
Unlike hyaluronic acid fillers, Ellansé cannot be dissolved or reversed. This is why it’s crucial to choose an experienced practitioner for your treatment. The effects will naturally diminish over time (18 months to 3+ years, depending on the type used) as your body gradually metabolizes the product.
How many syringes of Ellansé will I need?
The number of syringes required varies depending on the treatment areas and the degree of correction needed. For full-face rejuvenation, most patients need between 4-8 syringes. Your doctor will recommend the appropriate amount based on your individual needs.
Is Ellansé FDA-approved?
Ellansé is not currently FDA-approved in the United States. However, it has received CE marking in Europe (since 2009) and is approved by Singapore’s Health Sciences Authority (HSA). The components of Ellansé (PCL and CMC) are classified by the FDA as Generally Recognized As Safe (GRAS) substances.
Can Ellansé be used in all areas of the face?
Ellansé is versatile but not suitable for all facial areas. It works well for the cheeks, temples, jawline, chin, and nasolabial folds. However, it is not recommended for areas with thin skin such as the lips, under-eye area, and eyelids, as the collagen stimulation might cause visible lumps in these delicate regions.
Which type of Ellansé should I choose?
The choice between Ellansé S, M, and L depends on your desired longevity of results and treatment areas. Your doctor will recommend the most appropriate type based on your specific needs, age, and aesthetic goals. First-time users might start with Ellansé S or M before considering the longer-lasting Ellansé L.
How does Ellansé compare to Sculptra?
Both are collagen stimulators but work differently. Ellansé provides immediate volume plus gradual collagen stimulation, while Sculptra works entirely gradually. Ellansé typically requires just one treatment session, whereas Sculptra needs multiple sessions over several months. Ellansé results last 18 months to 3+ years; Sculptra results last about 2 years after completing the treatment series.
Can I exercise after getting Ellansé?
It’s recommended to avoid vigorous exercise for at least 3 days after Ellansé treatment to reduce the risk of increased swelling and bruising. Light activities are generally fine immediately after the procedure.
Who should perform Ellansé treatments?
Ellansé should only be administered by qualified medical professionals with specific training in its use—typically dermatologists, plastic surgeons, or aesthetic physicians with experience in facial anatomy and injectable treatments. Since Ellansé cannot be dissolved if complications occur, practitioner expertise is particularly important.
How can I prepare for my Ellansé treatment?
To minimize bruising and bleeding, avoid blood-thinning medications and supplements (like aspirin, ibuprofen, vitamin E, fish oil, and ginkgo biloba) for 1-2 weeks before treatment, if medically appropriate. Arrive at your appointment with a clean face free of makeup. Discuss your complete medical history and any medications you’re taking with your doctor before treatment.